NITROIMIDAZOLES VIII [I]. SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-PYRIDYL-NITROIMIDAZOLES
نویسندگان: ثبت نشده
چکیده مقاله:
Starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. From the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as prepared. Reaction of compound 15 with diazomethane gave I-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. The antibacterial and antifungal activities of compounds 5, 6, and 7 against a number of microorganisms were determined
منابع مشابه
nitroimidazoles viii [i]. syntheses, antibacterial and antifungal activities of 2-pyridyl-nitroimidazoles
starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. from the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as prepared. reaction of compound 15 with diazomethane gave i-methyl-2-(3-pyridy1)-5- nitroimidazol(e7 ) in addition to 6. the antibacterial and antif...
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عنوان ژورنال
دوره 1 شماره 3
صفحات -
تاریخ انتشار 1990-06-01
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